Medscape

Can valve replacement for asymptomatic aortic regurgitation wait until LV-dysfunction onset?

As the AVR indication in the study was the emergence of LV dysfunction by echocardiographydefined as the first detection of an LVEF <50%it suggests that delaying the surgery that long in asymptomatic ...
JSTOR Daily

Personalization of electro-mechanical models of the pressure-overloaded left ventricle: fitting of Windkessel-type afterload models

Laura Marx, Matthias A. F. Gsell, Armin Rund, Federica Caforio, Anton J. Prassl, Gabor Toth-Gayor, Titus Kuehne, Christoph M. Augustin, Gernot Plank https://www.jstor ...
JSTOR Daily

Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel

The heart pumps blood against the mechanical afterload from arterial resistance, and increased afterload may alter cardiac electrophysiology and contribute to life-threatening arrhythmias. However, ...
BMJ

Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise

1 MRC/UCT Research Unit for Exercise Science and Sports Medicine, Sports Science Institute of South Africa, University of Cape Town, South Africa 2 Centre for Sports Medicine and Human Performance, ...