The Indianapolis Colts have gone 1-5 in their last six games. Key players at impact positions are now out, and the team is ...

Find single game tickets to the San Francisco 49ers vs. Indianapolis Colts NFL Week 16 matchup on Monday, December 22, 2025 ...

Veteran Philip Rivers' improbable return from retirement ignites a thrilling road game as the 49ers face the surging Colts.

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are ...

The Colts are currently riding a four-game losing streak, which is the fourth-longest active streak in the league. If the ...

San Francisco 49ers quarterback Brock Purdy joins NFL Network's "Inside Training Camp Live" to provide a state of the team's ...

NFL Week 16 odds, picks, predictions, TV channel, streaming information for Monday Night Football between San Francisco 49ers ...

According to SportsLine's Inside the Lines team, Indianapolis on Monday night has much more to lose in Week 16 ...

INDIANAPOLIS — The Indianapolis Colts and San Francisco 49ers understand the stakes on Monday night. Both find themselves in ...

See who's in and who's out for the Week 16 matchup between the San Francisco 49ers and Indianapolis Colts on December 22, ...

USA Today's NFL experts make their picks for a Week 16 showdown between the Indianapolis Colts and San Francisco 49ers ...

San Francisco 49ers superstar tight end George Kittle opens up about facing 44-year-old Indianapolis Colts quarterback Philip Rivers.